EdenteV2, Main, Exploration, bibRecord, 00BC83

Scoring irradiation mucositis in head and neck cancer patients

Identifieur interne : 00BC83 ( Main/Exploration ); précédent : 00BC82; suivant : 00BC84

Scoring irradiation mucositis in head and neck cancer patients

Auteurs : F. K. L. Spijkervet [Pays-Bas] ; H. K. F. Van Saene [Royaume-Uni] ; A. K. Panders [Pays-Bas] ; A. Vermey [Pays-Bas] ; D. M. Mehta [Pays-Bas]

Source :

Journal of Oral Pathology & Medicine [ 0904-2512 ] ; 1989-03.

RBID : ISTEX:309C0739800CA555C04DE6D7531855168DDCA0E7

English descriptors

Abstract

Irradiation mucositis is defined as an inflammatory‐like process of the oropharyngeal mucosa following therapeutic irradiation of patients who have head and neck cancer. Clinically, it is a serious side effect because severe mucositis can cause generalized problems (weight loss, nasogastric tube feedings) and interferes with the well‐being of the patient seriously. Grading mucositis is important for the evaluation of preventive and therapeutic measures. The object of this study was to develop a scoring method based on local mucositis signs only. Four clinical local signs of mucositis were used in this score: white discoloration, erythema, pseudomembranes and ulceration. Mucositis of the oral cavity was calculated during conventional irradiation protocol for 8 distinguishable areas using the 4 signs and their extent. A prospective evaluation of this method in 15 irradiated head and neck cancer patients displayed an S‐curve reflecting a symptomless first irradiation week, followed by a rapid and steady increase of white discoloration, erythema and pseudomembranes during the second and third week. Oral candidiasis, generalized symptoms such as weight loss and the highest mucositis scores were seen after 3 weeks irradiation. The novel mucositis scoring method may be of value in studying the effect of hygiene programs, topical application of disinfectans or antibiotics on oral mucositis.

Url:

https://api.istex.fr/document/309C0739800CA555C04DE6D7531855168DDCA0E7/fulltext/pdf

DOI: 10.1111/j.1600-0714.1989.tb00756.x

Affiliations:

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Le document en format XML

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<author><name sortKey="Van Saene, H K F" sort="Van Saene, H K F" uniqKey="Van Saene H" first="H. K. F." last="Van Saene">H. K. F. Van Saene</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alimentation loss</term>
<term>Buccal mucosa</term>
<term>Candidiasis</term>
<term>Conventional irradiation protocol</term>
<term>Dent assoc</term>
<term>Discoloration</term>
<term>Distinguishable areas</term>
<term>Edentulous patients</term>
<term>Erythema</term>
<term>First week</term>
<term>Fourth week</term>
<term>Generalized symptoms</term>
<term>Hickey score</term>
<term>Highest mucositis score</term>
<term>Highest mueositis score</term>
<term>Intraobserver agreement</term>
<term>Irradiation mucositis</term>
<term>Irradiation protocol</term>
<term>Irradiation therapy</term>
<term>Local mucositis signs</term>
<term>Mouth floor</term>
<term>Mucositis</term>
<term>Mucositis score</term>
<term>Mucositis signs</term>
<term>Mueositis</term>
<term>Mueositis score</term>
<term>Nasogastric tube feedings</term>
<term>Neck cancer</term>
<term>Neck cancer patients</term>
<term>Oral candidiasis</term>
<term>Oral cavity</term>
<term>Oral complications</term>
<term>Oral hygienist</term>
<term>Oral mucosa</term>
<term>Oral mucositis</term>
<term>Oral pathol</term>
<term>Oral surg</term>
<term>Oral tissues</term>
<term>Ordinal scale</term>
<term>Particular area</term>
<term>Prosthet dent</term>
<term>Pseudomembranes</term>
<term>Radiotherapy</term>
<term>Several subareas</term>
<term>Steep slope</term>
<term>Study patients</term>
<term>Therapeutic irradiation</term>
<term>Third week</term>
<term>Weight loss</term>
<term>White discoloration</term>
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<term>Candidiasis</term>
<term>Conventional irradiation protocol</term>
<term>Dent assoc</term>
<term>Discoloration</term>
<term>Distinguishable areas</term>
<term>Edentulous patients</term>
<term>Erythema</term>
<term>First week</term>
<term>Fourth week</term>
<term>Generalized symptoms</term>
<term>Hickey score</term>
<term>Highest mucositis score</term>
<term>Highest mueositis score</term>
<term>Intraobserver agreement</term>
<term>Irradiation mucositis</term>
<term>Irradiation protocol</term>
<term>Irradiation therapy</term>
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<term>Mouth floor</term>
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<term>Mucositis score</term>
<term>Mucositis signs</term>
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<term>Mueositis score</term>
<term>Nasogastric tube feedings</term>
<term>Neck cancer</term>
<term>Neck cancer patients</term>
<term>Oral candidiasis</term>
<term>Oral cavity</term>
<term>Oral complications</term>
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<term>Particular area</term>
<term>Prosthet dent</term>
<term>Pseudomembranes</term>
<term>Radiotherapy</term>
<term>Several subareas</term>
<term>Steep slope</term>
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<front><div type="abstract" xml:lang="en">Irradiation mucositis is defined as an inflammatory‐like process of the oropharyngeal mucosa following therapeutic irradiation of patients who have head and neck cancer. Clinically, it is a serious side effect because severe mucositis can cause generalized problems (weight loss, nasogastric tube feedings) and interferes with the well‐being of the patient seriously. Grading mucositis is important for the evaluation of preventive and therapeutic measures. The object of this study was to develop a scoring method based on local mucositis signs only. Four clinical local signs of mucositis were used in this score: white discoloration, erythema, pseudomembranes and ulceration. Mucositis of the oral cavity was calculated during conventional irradiation protocol for 8 distinguishable areas using the 4 signs and their extent. A prospective evaluation of this method in 15 irradiated head and neck cancer patients displayed an S‐curve reflecting a symptomless first irradiation week, followed by a rapid and steady increase of white discoloration, erythema and pseudomembranes during the second and third week. Oral candidiasis, generalized symptoms such as weight loss and the highest mucositis scores were seen after 3 weeks irradiation. The novel mucositis scoring method may be of value in studying the effect of hygiene programs, topical application of disinfectans or antibiotics on oral mucositis.</div>
</front>
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Scoring irradiation mucositis in head and neck cancer patients

Scoring irradiation mucositis in head and neck cancer patients

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri